Thursday, 14th May The 3rd Prato Conference on Pore Forming Proteins 2015

• Dissecting the mechanism by which Staphylococcus aureus leukocidins target and kill host leukocytes - Victor Torres
• The staphylococcal Panton and Valentine Leukocidin and γ-haemolysin HlgC/HlgB share C5aR as a receptor, but operate diverse intracellular activities in human polymorphonuclear neutrophils - Emmanuel Jover
• The cholesterol-dependent cytolysis, pneumolysin and streptolysin O, require binding to red blood cell glycans for hemolytic activity - Michael P. Jennings
• Activity of pore-forming cholesterol dependent cytolysins assessed by dielectric damage of tethered bilayer membranes - Gintaras Valincius

• Staphylococcus aureus alpha-toxin:Complexities of the host-pathogen interaction - Juliane Bubeck Wardenburg
• Nutrient sensor GCN2 confers tolerance to bacterial pore forming toxins - Matthias Husmann
• A dominant-negative approach to combat Staphylococcus aureus pathogenesis - Tamara Reyes-Robles
• Failed CTL/NK cell killing and cytokine hyper-secretion are directly linked through prolonged synapse time - Joseph Trapani

• Unraveling how chromatin structure regulates cytotoxic T lymphocyte differentiation - Matthew Pipkin
• Plasma membrane attack by cholesterol-dependent cytolysins stimulates the internalization of the CDC-producing pathogen - Stephanie S.M.S. Seveau
• Heterozygosity for the common perforin mutation, A91V, impairs the cytotoxicity of primary natural killer cells from healthy individuals  - Imran G. House
• Dual roles for a novel pore-forming peptide toxin in the human fungal pathogen Candida albicans - Jonathan Richardson

Dinner location: Reffetorio di San Niccolo
Piazza Niccolo Cardinale, 6, Prato, Italy

Approximately 800 meter walk (10 mins) from Monash University.

The dinner will include a three course meal, drinks and tour of the Reffetorio di San Niccolo